May 05, 2007

A Grave Disease

From OverMyMedBody!
This just ain’t right. This guy must have some sort of malformation of his orbital ridge, or something, cause I have no idea how he’s getting his globe (eyeball) so far out. I think it’s real–you can see the lateral rectus muscle as the camera pans to the side…

I think this person has Grave's opthalmopathy. I don't know much about medicine yet, especially about the eyeball, but if you have a condition known as autoimmune hyperthyroidism aka Grave's disease, your eyes bug out like crazy! This happens because your body attacks the tissue behind your eyes and this triggers inflammation and an increase in glycosaminoglycan (GAG) production. It happens in the pretibial (shin) area as well. Here's a funny video I found on YouTube:

Grave's disease is typified by restlessness, irritability, hyperactivity, weight loss, muscle weakness, heart palpitations, eye problems, sweating and heat intolerance. For a clinical assessment of orbitopathy, click here. Pages 11-16 have some crazy pics of red, swollen eyes and stuff like that too.
Dickinson, A.J. Controversies in the clinical evaluation of active thyroidassociated
orbitopathy: use of a detailed protocol with
comparative photographs for objective assessment. Clinical Endocrinology (2001) 55, 283-303

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